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Gavi’s Board approves more than US$ 1.8 billion in support for African vaccine manufacturing

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…Establishes African Vaccine manufacturing accelerator

…The Board approved the inclusion of the new multivalent meningococcal vaccine into the Gavi portfolio, as well as the shortlist of new vaccines for Gavi’s next Vaccine Investment Strategy

…The Government of France and Africa CDC, alongside with European and international partners, will co-host a high level event in June 2024 to officially launch the AVMA mechanism as well as Gavi’s investment case to support its next replenishment

Friday, DEC 08 2023-theGBJournal|The Board of Gavi, the Vaccine Alliance on Thursday announced a series of decisions that will help lower-income countries tackle backsliding from the COVID-19 pandemic and be better prepared to respond to future health emergencies.

The decisions were taken during a two-day meeting hosted by the Government of Ghana in Accra, Ghana, from 6-7 December.

Following more than 18 months of close collaboration between Gavi, the African Union and Africa CDC, the Board also approved the establishment of the African Vaccine Manufacturing Accelerator (AVMA).

AVMA is an innovative financing mechanism aimed at establishing a sustainable African vaccine manufacturing industry capable of improving the region’s resilience in the face of pandemics, outbreaks and other health emergencies as well as the health of global vaccine markets.

AVMA was designed through an extensive consultation process that involved partners, donors, industry, civil society, and others.

Gavi, as one of the largest purchasers of vaccines in the world, is thus sending a powerful signal to global markets that it will support African vaccine manufacturing.

AVMA aims to make up to US$ 1 billion available to manufacturers at key moments in the development process as a way of helping offset high start-up costs and provide assurance of demand.

By focusing on “priority” antigens, product profiles, and vaccine platforms, as well as constructing clear incentives for both “fill and finish” and drug substance production, AVMA will also support global vaccine markets by targeting clear unmet needs and help establish a thriving, sustainable, end-to-end African vaccine manufacturing ecosystem.

AVMA is the final pillar of Gavi’s regional manufacturing strategy, with the first three pillars approved by the Board in December 2022.

With this Board approval, Gavi can now consult widely on the final operational framework for AVMA, including the establishment of an inclusive steering committee, and processes for governance, monitoring and course-correcting as needed.

These final pieces will be reviewed by the Board in June 2024, following which AVMA will be officially launched in that same month during an event co-hosted by France and Africa CDC, alongside with European and international partners.

“Today’s historic decisions illustrate the very best of our Alliance – collaboration across the full range of immunisation partners, constantly seeking to learn and improve, and most importantly, taking concrete action,” said Professor José Manuel Barroso, Chair of the Gavi Board.

“Gavi has worked closely with the countries, the African Union, Africa CDC, G7, G20, and other donors, WHO, UNICEF, civil society, industry, and experts to put into place innovative mechanisms that have the power to reshape our approach to regional manufacturing and pandemic response, and we are grateful for the continued commitment of our Board to the effort to ensure no one is left behind with immunisation.”

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